A Cartesian Fmm-Accelerated Galerkin Boundary Integral Poisson-Boltzmann Solver

نویسندگان

چکیده

The Poisson-Boltzmann model is an effective and popular approach for modeling solvated biomolecules in continuum solvent with dissolved electrolytes. In this paper, we report our recent work developing a Galerkin boundary integral method solving the (PB) equation. solver has combined advantages accuracy, efficiency, memory usage as it applies well-posed formulation to circumvent many numerical difficulties associated PB equation uses O(N) Cartesian Fast Multipole Method (FMM) accelerate GMRES iteration. addition, special treatments such adaptive FMM order, block diagonal preconditioners, discretization, Duffy's transformation are improve performance of solver, which validated on benchmark Kirkwood's sphere series testing proteins.

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ژورنال

عنوان ژورنال: Social Science Research Network

سال: 2022

ISSN: ['1556-5068']

DOI: https://doi.org/10.2139/ssrn.4203180